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Eukaryotic DNA topoisomerase I, catalytic core

class : alpha plus beta

number of structures : 2

average size : 231

average PID : 18 %

PDB code	start residue	start chain	end residue	end chain	name	source	resolution	R-factor
1a31	431	A	765	A	DNA topoisomerase I	Homo sapiens	2.1	24.7
1a41	81	-	310	-	DNA topoisomerase I	Vaccinia virus	2.3	22.7
pir \| ali \| malform \| joy-html \| colour postscript \| postscript \| superimposed coordinates (RasMol)

external links

PFAM : Topoisomerase_I

other info

key to JOY annotation | show related PDB structures

                           10        20        30        40        50  
1a31a  ( 431 )    pssrikgekdwqkYetArrLkkcVdkIrnqYredWksk-emkvrQrAVAL
1a41   (  81 )             nakrdriFvrVynvmkrIncfInknikksstdsnYQlAVFM
                            aaaaaaaaaaaaaaaaaaaaaaaa         aaaaaaa

                           60        70        80        90        100 
1a31a  ( 480 )    yFIDklaLragnekeegetadtvgCCsLrvehInlhpeldgqeyVVeFdf
1a41   ( 122 )    LMeTmf------fke----netvGlltLkNkhIeisp------deIvIkf
                  aaaa                         333  bb        bbbb b

                           110       120       130       140       150 
1a31a  ( 530 )    lgkdsiryynkvpVekrVFkNLqlFmenkqpeddLFdrLntgiLnkhLqd
1a41   ( 165 )    vgkdkvshefvvhksnrlykpLlkLtddsspeefLFnkLserkvyecikq
                  b     bb  bbb     aaaaaa                aaaaaaaaaa

                           160       170       180       190       200 
1a31a  ( 580 )    lmegLtAkvFrTYnaSitLqqqLke---lTapden-ipaKilSynrAnra
1a41   ( 215 )    f--gIrikdlrtYgvnytFLynFwtNVksisplpspkkLIalTikqTaev
                        aaaaaaaaaaaaaaaaaaa   a       aaaaaaaaaaaaaa

                           210       220       230       240       250 
1a31a  ( 626 )    v--kln--lDPRITVaWCkkw----gVpiekiynktqrekFawAidmAde
1a41   ( 263 )    vghtPsiskrayMatTIleMvkdknfldvVskTtfdeFlsiVvdhVks  
                            aaaaaaaaaa              aaaaaa aaaaaa   

                      
1a31a  ( 762 )    dyeF
1a41

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